One of the challenges in tissue engineering is the need for cell-size cages where cells can be encapsulated. A porous 3D structure of arbitrary geometry formed from biocompatible material is the perfect option for scaffold manufacturing.
Scaffold-like structure can be produced within a resolution of up to 150 nm capable of entrapping submicrometer sized cells by multiphoton polymerization (MPP) technique. MPP is a flexible technology that allows for the formation of various resolutions and different shaped structures.
Multi-photon polymerization (MPP) can be used for meta-material fabrication, including scaffolds for tissue engineering. The 3D gyroid structure is a mechanically rigid, light structure that can be fabricated by MPP, with a resolution up to 150 nm and capable of entrapping submicrometer sized cells.
Multiphoton-polymerization (MPP) is a technology that enables the production of arbitrary shape polymeric structures within submicrometric resolution. First, a photoresist sample is prepared by drop-casting polymer material mixed with a photoinitiator on the glass slide and then pre-baking.
A feasibility study is composed of several steps, including researching methods for fabricating micro-structures, fabricating a micro-structure prototype, measuring and aligning the prototype with technical requirements, and finally preparing a study report.